PHCY 879 - Molecular Basis of Xenobiotic-Induced Oxidative Stress-Mediated Toxicity and Its Clinical Implications
Oxidative stress has been recognized as an important mechanism associated with many diseases and contributes to xenobiotic-induced toxicity. This course provides an insight into the molecular mechanisms of oxidative stress including the key players, the intracellular signaling mechanism and the signaling consequences. Discussion includes the importance of the antioxidant defense mechanism in combating oxidative stress. In addition, the class examines commonly used over the counter drugs that result in oxidative stress-mediated toxicity and the factors that affect its toxicity due to modulation of antioxidant defense mechanism. Elective course.
Prerequisite(s): Pharmacy courses are only open to Pharmacy students.
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