May 09, 2025  
2024-2025 Course Catalog 
  
2024-2025 Course Catalog
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CHEM 535 - Biosynthesis of Nucleotides


3 Credits
Nucleotides are ubiquitous molecules essential for nearly every biochemical pathway, serving as substrates, regulatory molecules or monomers for RNA and DNA synthesis. Normal operations of all cells requires these molecules and cell growth is completely dependent on a ready source of nucleotides. Many medical conditions are the result of abnormalities in the pathways that synthesize nucleotides. The enzymes of these biosynthetic pathways are targets for pharmaceutical intervention. This course will provide an in-depth study of the biosynthesis of purine and pyrimidine ribonucleotides and their conversion to deoxyribonucleotides.
Prerequisite(s): CHEM 525 - Metabolic Biochemistry  



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